| Applications | WB,IHC,IF,ELISA |
|---|---|
| Species Cross-Reactivity | Human |
| Molecular Weight | Observed:42kDa Calculated:34kDa |
| Source | Rabbit |
| Isotype | IgG,Kappa |
| Recommended dilutions | WB :1:1000-1:5000 IHC: 1:200-1:1000 IF: 1:200-1:1000 ELISA: 1:5000-1:20000 Optimal dilutions should be determined by the end user |
| Purification | Protein A |
| Specificity | Endogenous |
| Alternative Names | NANOG ; Homeobox protein NANOG ; Homeobox transcription factor Nanog ; hNanog |
| Gene Id | |
| Swiss Prot No | |
| RRID | AB_3740140 |
| Subcellular Location | Nucleus |
| Expression | Expressed in testicular carcinoma and derived germ cell tumors (at protein level). Expressed in fetal gonads, ovary and testis. Also expressed in ovary teratocarcinoma cell line and testicular embryonic carcinoma. Not expressed in many somatic organs and oocytes. |
| Background | The protein encoded by this gene is a DNA binding homeobox transcription factor involved in embryonic stem (ES) cell proliferation, renewal, and pluripotency. The encoded protein can block ES cell differentiation and can also autorepress its own expression in differentiating cells. Two transcript variants encoding different isoforms have been found for this gene. |
| Storage Buffer & Condition | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA Store at -20°C. Stable for 12 months from date of receipt |
说明书.pdf
