| Applications | WB,IHC,IF,IP,ELISA |
|---|---|
| Species Cross-Reactivity | Human,Mouse,Rat |
| Molecular Weight | Observed:78kDa Calculated:78kDa |
| Source | Rabbit |
| Isotype | IgG,Kappa |
| Recommended dilutions | WB :1:1000-1:5000 IHC: 1:200-1:1000 IF: 1:200-1:1000 IP: 1:50-1:200 ELISA: 1:5000-1:20000. Optimal dilutions should be determined by the end user |
| Purification | Protein A |
| Specificity | Endogenous |
| Alternative Names | Long-chain-fatty-acid--CoA ligase 4 ;Long-chain acyl-CoA synthetase 4 ; LACS 4 ; |
| Gene Id | |
| Swiss Prot No | |
| RRID | AB_3712038 |
| Subcellular Location | Membrane |
| Background | The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme preferentially utilizes arachidonate as substrate. The absence of this enzyme may contribute to the cognitive disability or Alport syndrome. Alternative splicing of this gene generates multiple transcript variants. |
| Storage Buffer & Condition | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA Store at -20°C. Stable for 12 months from date of receipt |
说明书.pdf
