| Applications | WB, IHC |
|---|---|
| Species Cross-Reactivity | H,M,R |
| Molecular Weight | 68KD(45KD) |
| Source | Rabbit |
| Isotype | IgG |
| Recommended dilutions | WB: 1:1,000-3,000 IHC: 1:500-1,000 Optimal dilutions should be determined by the end user |
| Specificity | The Lamin B1 antibody can detects endogenous Lamin B1 protein. |
| Alternative Names | ADLD, LMB1,LMNB1, MGC111419, OTTHUMP00000159218 |
| RRID | AB_3711202 |
| Background | The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. This gene encodes one of the two B type proteins, B1. |
| Storage Buffer & Condition | PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50%Glycerol. Store at -20°C. Do not aliquot the antibody. |
说明书.pdf
