| Applications | WB,IF |
|---|---|
| Species Cross-Reactivity | H, R, M |
| Molecular Weight | 15KD |
| Source | Mouse |
| Isotype | IgG1 |
| Recommended dilutions | WB: 1:1,000-3,000 IF: 1:100-200 Optimal dilutions should be determined by the end user |
| Specificity | Antibody can detects endogenous COX IV protein. |
| Alternative Names | COX 4, Cox4a, COX4B, COXIV, Cytochrome c oxidase subunit 4 isoform 1 mitochondrial, MGC105470, dj857M17.2, Cytochrome c oxidase subunit IV |
| RRID | AB_2891318 |
| Background | The enzyme cytochrome c oxidase or Complex IV, EC 1.9.3.1) is a large transmembrane protein complex found in bacteria and the mitochondrion.It is the last enzyme in the respiratory electron transport chain of mitochondria (or bacteria) located in the mitochondrial (or bacterial) membrane. It receives an electron from each of four cytochrome c molecules, and transfers them to one oxygen molecule, converting molecular oxygen to two molecules of water. In the process, it binds four protons from the inner aqueous phase to make water, and in addition translocates four protons across the membrane, helping to establish a transmembrane difference of proton electrochemical potential that the ATP synthase then uses to synthesize ATP. |
| Storage Buffer & Condition | PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50%Glycerol. Store at -20°C. Do not aliquot the antibody. |
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