Applications | WB,IHC |
---|---|
Species Cross-Reactivity | Human,Mouse,Rat |
Molecular Weight | 21kDa |
Source | Rabbit |
Isotype | IgG |
Recommended dilutions | WB: 1:1000-1:2000 IHC: 1:100-1:200 Optimal dilutions should be determined by the end user |
Specificity | Antibody can detects endogenous P21 protein. |
Alternative Names | CDKN1 antibody, CDKI antibody, CDKN1A antibody, MDA 6 antibody, p21 cip1 antibody, p21waf antibody |
Background | p21 / WAF1 / CIP1 also known as cyclin-dependent kinase inhibitor 1 or CDK-interacting protein 1 is a protein that in humans is encoded by the CDKN1A gene. p21 is a potent cyclin-dependent kinase inhibitor (CKI). The p21 (CIP1/WAF1) protein binds to and inhibits the activity of cyclin-CDK2, -CDK1, and -CDK4/6 complexes, and thus functions as a regulator of cell cycle progression at G1 and S phase. |
Storage Buffer & Condition | Antigen Affinity Purified IgG in PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol. Store at -20°C. Stable for 12 months from date of receipt |